Louisville vs. Ole Miss 2026 Season Opener: Game Preview and Broadcast Details
The Louisville football team's 2026 season-opener against Ole Miss has been scheduled for Sunday, September 6 at 7:30 p.m. EST at Nissan Stadium in Nashville, Tennessee. The game will be broadcast on ABC, making it a highly anticipated matchup. This game will be one of only two games played on the Sunday of Labor Day Weekend, with Notre Dame-Wisconsin being the other game at Lambeau Field.
Both Louisville and Ole Miss are expected to be top-25 teams when they face off in this season opener. Despite losing head coach Lane Kiffin, Ole Miss had a successful 2025 season, making a run in the College Football Playoff. Led by quarterback Trinidad Chambliss, the Rebels are looking to continue their success under new head coach Pete Golding.
Louisville, under head coach Jeff Brohm, had a strong 2025 season with a 9-4 record. The Cardinals have consistently performed well under Brohm's leadership, winning at least nine games in each of the past three seasons. With key players returning and a strong portal class, Louisville is poised for another successful season in 2026.
This matchup between Louisville and Ole Miss will be only the second time these teams have faced each other. The previous meeting resulted in a victory for Ole Miss in the Chick-Fil-A Kickoff Game in 2021. With both teams looking to start the season strong, this game is sure to be an exciting one for college football fans.